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KMID : 0604520170430030211
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Journal of the Society of Cosmetic Scientists of Korea
2017 Volume.43 No. 3 p.211 ~ p.221
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Antibacterial, Antioxidant, and Antiaging Effects of the Ethanol Extract of Dolnamul (Sedum sarmentosum) and the Production of the Oil in Water Cream
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Kim Young-Dae
Kim Young-Min
Mo Eun-Kyung
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Abstract
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This study was performed to investigate the functional properties and characteristics of Dolnamul (Sedum sarmentosum)
as a cosmetic ingredient. Lyophilized sedum powder was extracted with ethanol and stored at －20 ℃ for the following experiments. Total polyphenol compounds of the ethanol extract of sedum (SE) was 27.98 ± 0.34 g/kg (dry weight): epicatechin (162.14 ± 5.07 mg/kg), epigallocatechin (55.99 ± 2.49 mg/kg), and kaempferol (47.96 ± 3.02 mg/kg) were contained in the SE. The SE had organic radical scavenging capacity (78.43 ± 1.08%) and metal reducing power (FRAP value 2.54 ± 0.12). FTC and TBARS assays confirmed that the SE inhibited the early stage of lipid peroxidation (62.03 ± 0.38%) as well as the final stage of lipid peroxidation (55.36 ± 2.05%), respectively. The SE (5 mg/mL, dry weight) was proved to have antibacterial effect on the growth of Propionibacterium acnes. The inhibitory percentages of the SE on elastase and collagenase activities were 38.94 ± 7.09% and 78.94 ± 2.49%, respectively. Compare to the control group, the SE treated group induced an increase of Col3A1 expression and collagen production (58.11 ± 1.07%). The oil in water emulsion (0.5% SE adding group) showed pH 6.88 and 1.47 g/mL of density. The hardness changes of the SE adding emulsions were not detected during the stored periods at various temperatures (－20 - 45 ℃) for four weeks. It is considered that the SE has antibacterial, antioxidant, and antiaging activities.
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KEYWORD
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Sedum sarmentosum , Propionibacterium acne , Col3A1 , epicatechin , antiaging
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